Seroprevalence of Toxoplasma gondii in children: A systematic review and meta-analysis.

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Toxoplasma infection during childhood may cause severe effects for children and the next offspring if does not treat. Here, we initiated a systematic review to estimate the global prevalence of Toxoplasmosis in Iraqi children. From all databases for articles published between January 2000 and March 2021 and included studies that related the prevalence of Toxoplasma gondii in children (1 day – 15 years), the overall prevalence rate of Toxoplasmosis was evaluated with a 95% CI in globally and WHO regions. This result was performed as linear regression analyses to detect associations of the prevalence of Toxoplasmosis with the overall population number. As a result, 63 articles included 29342 children from 18 countries incorporated in the systematic analysis. The total globally prevalence rate of Toxoplasma in children was 0.2% (95% CI: 0.195 – 0.204 %). The prevalence rate was so highest in the Africa region 0.28 % (95%CI: 0.5- 0.55%) and lowest in the South America and USA regions 0.166% (95% CI: 0.01 – 0.33%). The prevalence rate among children is very high when compared with other groups of the population. These results require further examination and investigation of the parasite among children to reduce new infections occurrence or prevent complications of the disease.
Toxoplasma gondii; Seroprevalence; Children; Meta- analysis; Systematic review
Musafer H. A-Ardi Received 12-20-2021, Accepted 02-07-2022, published 05-31-2022.
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