Synthesis, Identification and Assess the Biological and Laser Efficacy of New Compounds of Azetidine Derived from Benzidine

Adil Hussein Dalaf1 and Fawzi Hameed Jumaa2

 1Department of Chemistry – College of Science – Tikrit University. Tikrit-Iraq

2Department of Chemistry – College of Education for Women – Tikrit University. Tikrit-Iraq

*Corresponding Author: adil.h.dalaf@tu.edu.iq

DOI: 10.18081/2226-3284/14-10/12-25

Adil Hussein Dalaf1 and Fawzi Hameed Jumaa2 1Department of Chemistry – College of Science – Tikrit University. Tikrit-Iraq 2Department of Chemistry – College of Education for Women – Tikrit University. Tikrit-Iraq *Corresponding Author: adil.h.dalaf@tu.edu.iq DOI: 10.18081/2226-3284/14-10/12-25
HighlightsAbstractKey words
Preparation of heterocyclic compounds with new pharmacological properties. Preparation of organic compounds with high biological activity against bacterial germs. Diagnosis of prepared compounds by physical and spectroscopic methods. Spectroscopic and physical measurements validated the prepared compounds. Studying the effect of lasers on these compounds, as it has been proven that the rays do not affect them.
In this study, new azetidine [A1-A5] compounds were prepared by the reaction five of schiff bases compounds with chloroacetyl chloride in 1,4-dioxane. The prepared compounds were characterized by physical properties, UV-Vis, 1H-NMR and FT-IR spectral and C.H.N analysis. TLC checked the purity for these compounds. The antibacterial activities were studied against different kinds of bacteria, namely Staphylococcus epidermidis and Staphylococcus aureus Gram (+) ve, Eschershia coli, and Klebsiella Pneumonia Gram (-) ve. Also, evaluation of laser efficacy is shown for the compounds (A1-A5) were laser radiated to (10, 20, 30) seconds. When the melting point and color were measured, it was found that the compounds were not affected or polymerized.
Benzidine, Azetidine, Biological activity, Laser Effectiveness.

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