treatment of the cardiovascular system diseases, the current study focused to investigation the histo logical and bio chemical
change in the kidney of male white mice after being treated with warfarin for 30 day. The present work carryout 40 males
white mice, all laboratory animals were housed in the animal house of the sciences college / AL-Muthanna University. The
experimental animals were divided into two groups which including group A was consider as control group, group B was
treated with warfarin. The results after treated time with warfarin, showed prominent damage in renal corpuscle, the
mechanism leading to renal damage is glomerular and tubular hemorrhage, spot of hemorrhage in parenchyma of the
kidney and cystic dilation filled with blood. The biochemical results noted significantly increase in the levels of urea and
crietinine comparation with control group. In conclusion, the warfarin was effective in treating blood clots, but it has side
effects on the kidneys. (Valium)
Noora A. Hassan1 , Bassim Abdullah Jassim2
Received 28-9-2021, Accepted 26-10-2021, published 31-12-2021.
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